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In vitro toxicity studies are laboratory-based assessments performed outside of living organisms, using systems such as cultured cells, tissue slices, or organotypic models. These studies aim to determine the toxic effects of substances at the cellular and molecular levels, offering valuable insights into their mechanisms of action. They are widely used in the early stages of safety evaluation and serve as a foundation for identifying potential hazards before advancing to in vivo testing.
Key features of in vitro toxicity studies include:
Use of non-animal models: Helps reduce reliance on animal testing by providing ethical and efficient alternatives.
Cellular and molecular focus: Assesses how substances affect cell viability, gene expression, and biochemical pathways.
Early safety screening: Identifies toxic compounds early in product development, saving time and resources.Regulatory and research relevance: Supports regulatory decision-making and enhances understanding in toxicological research.
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