Leading Service provider for Abnormal Toxicity Studies, Acute Toxicity Studies, Allergic Toxicity Studies, Carcinogenicity Toxicity Studies, Chronic Toxicity Studies, Ecotoxicology Studies, Invitro Toxicity Studies, Irritation Toxicity Studies, Medical devices testing, Pharmacological Toxicity Studies, Reproductive Toxicity Studies, Sub Acute Toxicity Studies and Supplementary Toxicity Studies.
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We here at Toxicity are trusted name for acute toxicity testing. The acute toxicity testing is normally done by giving a single dose to animals. Our acute toxicity study is widely acknowledged and because of its huge demand we have acute toxicity testing in South Africa also.
Acute Toxicity Studies are also carried by us to determine the toxic manifestation of various substances. This research is conducted on an animal, which is exposed to a lot of doses of test substances in the span of 24 hours for studying the toxicity. One is acquainted with the health hazard that can be caused by the substance in question.
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We are providing services for Allergic Sensitization Studies. Repeated exposure of a test substance can activate the immunological system that can be activated by prior exposure and the response may be characterized by various external factors like erythema, edema, nasal discharge, tearing etc. This study gives information regarding the sensitization of the immune system towards a particular compound.
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Our institute provides the study of the Carcinogenicity and Mutagenicity. The main objective behind the study of carcinogenicity is to find out the effects of the test compounds whenever exposed for a long period of time. The objective behind the study of the mutagenicity is to study the adverse effect that has been caused by any compound or any chemical on the cell’s genetic material which is the DNA.
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Various toxicity tests/toxicity testing can be performed to assess the chronic toxicity of different contaminants. Results after chronic toxicity testing on a product/ organism can be used to determine the guidelines and regulations for protection of organisms.
Chronic Toxicity testing of new compounds is essential for the drug development process. The chronic toxicity testing on various biological systems reveals the species toxic effects of the tested product. The toxicity of substances can be observed by
We at toxicity are renowned for the best toxicity testing services. Here, we provide toxicity testing services for the chronic toxicity in the product. The chronic toxicity is developed because of adverse effect long term exposure to a toxicant or other stressor. It results in decrease of growth, reduced reproduction, or behavioral changes.
The chronic toxicity testing results related to toxicant is important to know to determine the water quality. Chronic toxicity tests are costly and difficult. The various difficulties are due to various challenges which are related to keeping control and keep organisms alive, maintaining water quality, retain constant chemical exposures, and time needed for tests. Because of this, acute toxicity tests we here have an expertise team who conduct ACRs and AFs test to know chronic toxicity of toxicants to organisms.
Chronic Toxicity is done to characterize the profile of a substance in a mammalian species following prolonged and repeated exposure. The routes of exposure are most likely the ones to which the human are exposed to that particular compound.
We at Toxicity India have expertise that follows the testing method with all the safety measures and follow all the standard of the performance of chronic toxicity testing. We at Toxicity assure to give an appropriate result which is giving us recognition among the top chronic toxicity testing laboratories. It is because of our scientific in-depth knowledge that we promise the most appropriate results. Chronic toxicity tests are expensive for the pockets and challenging for the investigator as the control is kept on the alive organism maintaining water quality, retaining constant chemical exposures and the time required for the tests.
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A modern, well equipped necropsy laboratory for Ecotoxicology Studies that provides complete bacteriology, histopathology, clinical pathology, parasitology, tissue banking, and customized studies for a wide range of laboratory including Bee toxicity, Fish toxicity, Toxicity to birds. The lab’s focus is on client service, quality results, and rapid turnaround times.
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Our scientists and research associates help in conducting Invitro Toxicity Studies. We are one of the renowned and reputed institutes engaged in providing highly reliable research related services. Our toxicity studies are considered crucial in understanding the toxicity level. These researches and studies help spread awareness and one can avoid exposure to these toxic compounds or chemicals. Level at which these elements can cause health hazard is also studied by us.
Product Code | RDIT01 |
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IRT is renowned for research and toxicology of the Irritation Studies. The Skin Irritation testing is to determine if a material or device with which a patient body would have to contact is irritant or not. We at Toxicity testing conduct the skin irritation testing to measures the reaction to single, repeated, or continual exposure on skin from the tested device materials which can be a cause of skin irritation, resulting in mucosal, or ocular irritation.
Prevention is better than the cure. Skin is the most easily effective part of human body in terms of infection. Skin irritation test is the popular test which is done to ensure safety and analyse the risk assessment of the products and its components on the skin. The skin testing is vital in the countries like India, Africa and Kenya. Toxicity testing in South Africa is done on all and various products. The toxicity testing involves basic testing and advance or specific testing which is specific to the place or region, depending upon the climatic condition there etc. The skin irritation test is the basic requirement needed to be done to ensure the product safety on human body before the introduction of the product to the market. Earlier the skin testing was done by using the product or doing a practical experiment on animals. With science advancement, the approach of toxicity testing has changed, and no more harm or damage is done on animals for doing skin testing of the product. The skin corrosion, skin irritation testing and risk assessment are implemented without using any test methods on animals. The vitro test or novel acute irritation patch tests in human are the popular and in demand skin irritation test at toxicity. An array of other human test methods has developed and used for the chronic skin irritation and the general skin compatibility of the finished products. IIRT is a renowned and trusted research Centre for irritation testing and irritation study. The institute is renowned for its toxicity testing services in South Africa, Kenya and India.
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We under take the Biocompatibility testing as per ISO10993 for the medical devices
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Our institute is providing the Pharmacological Study Services and that includes the Oxidative stress study, invitro haemolysis test, anti-hypersensitivity and Hypersensitivity activity studies, Immuno- modulatory activity of the compounds, hepatoxic, hepatogenic and Hepatoprotective effects of drug and hypocholestrimic and Hypoglycemic effects of drugs. The important aspects of the pharmacological study are that they are the use of drugs for studying physiological mechanisms and they are the use of drugs as medicines.
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The pyrogen test is a critical assay conducted in the pharmaceutical and biomedical industries to assess the presence of pyrogens in pharmaceutical products, medical devices, and biological substances. Pyrogens are substances, typically endotoxins derived from the outer membrane of Gram-negative bacteria, that can induce fever when introduced into the bloodstream.
Regulatory agencies mandate the pyrogen test as part of the safety evaluation process for pharmaceutical products and medical devices. Compliance with these regulations is essential for obtaining approval for product registration and market authorization.
Application | Agriculture, Gardening, Public Health, Seed Treatment, Soil Amendments |
Feature | Anti Bacterial |
Form | Dust, Liquid Concentrate, Powder |
Country of Origin | India |
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New genetic technologies are increasingly being used in the clinical testing; the need for this is to ensure the discourse on the ethical use of the products on the offspring. The greatest urgency in reproductive toxicity study is the genetic testing. The main reason for the increasing demand of this test is the increasing commercialization and expanding scope of noninvasive prenatal testing. The study done on the commodity/ product is to ensure that there are no possible threats neither on disability nor on genetic diversity on consumption of the same. Reproductive toxicity testing reports ensures thorough acknowledgment from clinicians, researchers who are expertise in genetics. Reproductive toxicity testing is a highly sensitive test and we here surely understand the “dangers of oversimplification” therefore in hypothetical scenarios, giving full consideration to our social responsibility our reports also address the common misconceptions about the human genome and about the capabilities of some reproductive genetic technologies. It is our detailed report and our latest technology usage that has made us the renowned and trusted name for reproductive toxicity testing in South Africa. We at IIRT have exxtended ourselves and has gained the popularity as the trusted reproductive toxicity testing service provider in India, South Africa and Kenys.
GENETIC UNCERTAINTY AND THE BLURRED LINE BETWEEN DIAGNOSIS AND SCREENING FOR RISK
The journey from genotype (the genetic makeup of an individual) to phenotype (their observable characteristics) is complicated. Genetic uncertainty is because of incomplete knowledge and the operating process at biological organization. The rapid pace of advances in our understanding of the human genome because of the constant in depth reproductive toxicity study has enhanced our knowledge on the genetic information which results in thorough understanding on the normality and abnormality for genotypes, phenotypes, and people. Instead, in new reproductive toxicity testingtechnology we also ensure to know the degree to which the specific mutations influence the severity of the clinical presentation on the body affects. We also do detail studies to see how different individuals with the same mutations, even within a family, can have major differences in illness severity. For most common conditions like neuropsychiatric disorders, cancer etc the focus is shifting from individual genes to genetic pathways.
We at toxicity continuously strive to better understand these phenomena, with the objective of improving the genetic testingwith our in-depth knowledge and reproductive toxicity studies. Our reports are to take complete care and keep uncertainty in consideration as different couples will make different reproductive decisions on the same information.
GENE–GENE INTERACTIONS, INTERCONNECTED NETWORKS, AND QUANTITATIVE TRAITS
Our continued study of the human genome, and of its impact on health and disease, has revealed that just like disability exists along a continuum, so too do common quantitative traits, including some of the “cosmetic” traits. The result is multi factorial effects on highly dynamic, interdependent, nonlinear biological networks. To explain lets consider the simplest and most concern trait likeIQ and height. Reproductive genetic studies are, in general terms, capable of influencing these to a certain extent. The detailed investigan and report accuracy has made us a renowned and trusted name for reproductive toxicity testing in South Africa.
DECISION MAKING IN THE ERA OF GENOMIC MEDICINE
The relationship between disability and genetics is complicated. and the possibility that advances in genetics might be put to unethical use is a legitimate concern. Taking care of all the technical considerations, we not only see the desired outcomes but also emphasize on the effect reproductive genetic effect with full consideration on both practical and immutable uncertainties. This makes “a world of striking uniformity” seem less likely. We all understand that the uptake of technologies somewhere leaves an impact on human genes. Therefore, our reproductive toxicity testing also depends on the place which includes climatic condition etc. We are the renowned as centre for reproductive toxicity testing in Kenya ans South Africa. It is our investigation procedure and the expertise team which has made us renowned not only in India but also gave us pride because of our recognition in reproductive toxicity testing in South Africa.
IIRT is the trusted reproductive testing centre assuring the authentic report made by expertise with each and every possible consideration. Our expertise of Reproductive toxicity testing assures that all the standards are met. Send us an enquiry below for any kind of reproductive toxicity testing in India, South Africa and kenya. Our team of expertise will revert you at the earliest with best of the answer to your queries as per the teams knowledge and experience.
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The sub-acute toxicity studies are aimed at finding out the toxic effect of a drug on constant exposure. Sub-acute toxicity studies also gives the valuable information about the delayed effect that might be the result for cumulative effect of chemicals. This study helps in understanding the height of safe usage of the compound. The Chronic Toxicity Studies are aimed at characterizing the effects of the compounds that are being tested. The exposure of the route are the ones on which humans are exposed. Days of study: 28 days.
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Our renowned institute of toxicity study is offering the Supplementary Toxicity Studies. This study includes ICH Guidelines, OECD Guidelines for testing of chemicals, Gaitonde Committee Protocol, Regulations of Central Insecticides Board, Neurotoxicity studies on Egg laying hens, Schedule Y of Drugs and Cosmetics Act, Synergism & Potentiation Studies are the combined effects of several chemicals. These supplementary toxicity studies are very important to know the toxicity level of a compound or chemical.
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