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Systemic toxicity studies are conducted to evaluate the adverse effects of a substance on the entire body or specific organ systems following its absorption into the bloodstream. These studies help determine how a substance affects various physiological functions and organ health over time. They are a critical component of safety assessments for a wide range of products and substances.
These studies are important for evaluating the safety of:
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Pharmaceuticals – to ensure drugs do not cause harmful effects at therapeutic doses
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Chemicals – including those used in agriculture, industry, or cleaning products
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Food additives – to verify safety for human consumption over time
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Cosmetics – especially products absorbed through the skin
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Industrial compounds – to assess occupational and environmental exposure risks
Systemic toxicity studies provide essential data for regulatory agencies to set exposure limits, labeling requirements, and usage guidelines to protect human and environmental health.
