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Cytotoxicity studies are laboratory tests conducted to assess the harmful effects of a substance on cultured cells. These studies help determine whether a chemical, drug, or other material can damage cells, inhibit their growth, or cause cell death. Cytotoxicity testing is a key step in the early stages of product development, particularly for pharmaceuticals, cosmetics, medical devices, and environmental chemicals.
These studies are essential for:
Screening new compounds – to identify toxic effects before animal or human testing.
Evaluating cell viability – measuring the ability of cells to survive after exposure.
Detecting cell damage – including membrane disruption or organelle injury.
Assessing dose-response relationships – to determine the concentration at which a substance becomes harmful.
Ensuring product safety – especially in cosmetics, where human testing may be limited.
Cytotoxicity assays, such as MTT, LDH release, or Trypan Blue exclusion, provide quick, cost-effective, and ethical methods to predict potential toxicity.
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